摘要

       The high-resolution brain mapping and digital brain atlases in primates based on MRI and histology is of great value in anatomical, functional, and clinical studies. In particular, a 3D atlas can be registered to a brain MRI volume to best determine the regions of interest for anatomical tracer injections for brain connectivity studies, the areal location of observed functional activation areas in functional imaging (fMRI) studies, and the potential targets for deep brain stimulation in non-human primate models of neurological disorders.

    In my talk, I will introduce comprehensive brain atlases constructed from three well known and extensively studied primate species: Macaque, Marmoset, and Human. These high-resolution brain atlases in these species were constructed based on high-dimensional multimodal MRI and histology with multiple stains.

    The cross-species of comparison of brain areas in these primate species is important for our understanding of brain structure-function relationship.

 个人简介 

      Dr. Kadharbatcha Saleem is a Senior Scientist at the National Institute of Health (NIH) with major research experience in systems/cognitive neuroscience, cell and circuit-based tools, behavioral neuroscience, anatomical and functional neuroimaging (MRI/fMRI), neurosurgery, 3D digital brain atlases, connectome, and diffusion MRI tractography in non-human primates, and brain disorders in human. Dr. Saleem was involved in scientific peer review process of different study sections, including the BRAIN initiative targeted brain circuit projects; Neuropsychiatric and other Brain Disorders; and Clinical Neurological Disorders and Aging. He has extensive experience in teaching graduate level neuroscience courses and research program management, and leadership and consultant role in a wide area of neuroscience research program. Dr. Saleem has extensive publication record in leading scientific journals and books.