Neuroimaging and Brainnetome Laboratory focuses on genetically engineering mice brainnetome with neuroimaging, especially 9.4T and 16.4T MRI scanners, and other techniques. It is a collaboration platform between Institute of Automation of the Chinese Academy of Sciences (CASIA) in Beijing and Queensland Brain Institute, University of Queensland, Australia. It closely collaborates with Brainnetome Center at CASIA in Beijing and its branch at the University of Electronic Science and Technology in Chengdu, to study basic theory, methodologies and algorithms, platform of the Brainnetome at multiple scales, and their applications in neurological and psychiatric diseases.
We explore the mechanisms of brain disorders by studying genetically engineering mice brainnetome with neuroimaging, especially 9.4T and 16.4T MRI scanners, and other techniques. Convergent evidence has shown that brain functions can manifest on brain networks on different scales and brain malfunctions caused with most psychiatric disorders are faulty brain networks. In order to understand how the brain works and the pathophysiological mechanism of psychiatric disorders, it is necessary to integrate the multi-level network features obtained with various functional and anatomical brain imaging technologies on different scales. We have proposed a new concept of “Brainnetome” (www.brainnetome.org) to represent such integration framework. We define the essential components of brainnetome as identification of brain networks. (connectome), dynamics and characteristics of brain networks, network manifestation of functions and malfunctions of the brain, genetic basis of brain networks, and simulating and modeling for the Brainnetome. It envisions that Brainnetome will become an emerging co-frontier of brain imaging, information technology, neurology and psychiatry. Some long-standing issues in neuropsychiatry may be solved by combining Brainnetome with genome.